Interventions for paracetamol (acetaminophen) overdose
نویسندگان
چکیده
منابع مشابه
Interventions for paracetamol (acetaminophen) overdose.
BACKGROUND Paracetamol (acetaminophen) is the most widely used non-prescription analgesic in the world. Paracetamol is commonly taken in overdose either deliberately or unintentionally. In high-income countries, paracetamol toxicity is a common cause of acute liver injury. There are various interventions to treat paracetamol poisoning, depending on the clinical status of the person. These inter...
متن کاملThe spectrum of paracetamol (acetaminophen) overdose: clinical and epidemiological studies.
In a regional survey of paracetamol overdose, 201 patients were admitted to hospital over 12 months. Chronic alcoholism was present in 10% of cases. Over 25% of patients were females aged 20 years or less. Initial blood paracetamol levels were in the toxic range in 16% and histologically severe liver damage eventually found in 20% of those biopsied. This finding corresponded to a serum aspartat...
متن کاملAcetaminophen overdose in Jamaica.
Acetaminophen is a dose dependent hepatotoxin which is frequently associated with intentional self-harm. Forty-nine cases of parasuicide attempts involving paracetamol only or in combination with another drug were treated at the UHWI, Jamaica, between 1994-2004. The majority were women (84%) and the mean age was 23 years. Acetaminophen was the only agent ingested in 71% of cases; 29% involved a...
متن کاملLiver transplantation after paracetamol overdose.
OBJECTIVE To evaluate the role of liver transplantation after paracetamol overdose. DESIGN Prospective study of consecutive candidates for transplantation and performance of transplantation over 18 months. SETTING Liver unit, King's College Hospital, London. MAIN OUTCOME MEASURES Fulfilment of indicators of poor prognosis, selection for transplantation, transplantation, survival. RESULT...
متن کاملSevere thrombocytopenia after paracetamol overdose.
Two patients with severe thrombocytopenia after paracetamol overdose are described. The platelet count was lowest two days after the overdose. Neither leucopenia nor anaemia occurred.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2018
ISSN: 1465-1858
DOI: 10.1002/14651858.cd003328.pub3